Transcriptome profiling of human oocytes experiencing recurrent total fertilization failure

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P-102: Recurrent In Vitro Fertilization Failure and Hereditary Thrombophilia

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Total fertilization failure and idiopathic subfertility

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Transcriptome Profiling of Human Pre-Implantation Development

BACKGROUND Preimplantation development is a crucial step in early human development. However, the molecular basis of human preimplantation development is not well known. METHODOLOGY By applying microarray on 397 human oocytes and embryos at six developmental stages, we studied the transcription dynamics during human preimplantation development. PRINCIPAL FINDINGS We found that the preimplan...

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The aim of the study was to assess the fatty acid composition of human fertilization-failed oocytes. A total of 150 unfertilized oocytes from 43 women undergoing in-vitro fertilization (IVF) were analysed using capillary gas chromatography. The majority of fatty acids were saturated (79.22%), of which stearic (38.65%) and palmitic (32.66%) acids were the most abundant. Of the monounsaturated fa...

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ژورنال

عنوان ژورنال: Scientific Reports

سال: 2018

ISSN: 2045-2322

DOI: 10.1038/s41598-018-36275-6